Leave it to Mark Millar to screw it up when he's got a good thing going. Even without the terrible soft cliffhanger, MPH does have some fantastic art from Duncan Fegredo. Fantastic enough to probably make the comic worth a look even if it didn't have a serviceable script.
There are all the standard Millar problems. It's too self-aware, the pop culture references are too forced, probably a few other things but I ignored them. However, Millar does write a good first person narration for his protagonist. It's some small time crook who ends up in prison for a relatively small crime and then gets superpowers.
The superpowers come from a pill called MPH. There's going to be an idiotic explanation for it, which the soft cliffhanger foreshadows. Still, the way Millar shows the guy's experience is fantastic.
The comic's predictably problematic (given Millar) but it's better than expected.
Writer, Mark Millar; artist, Duncan Fegredo; colorist and letterer, Peter Doherty; editor, Jennifer Lee; publisher, Image Comics.